Salmeterol 25mcg + Fluticasone Propionate 50mcg
Salmeterol: Selective long-acting β2-agonist that relaxes airway muscles and prevents symptoms for up to 12 hours.
Fluticasone Propionate: Inhaled corticosteroid with anti-inflammatory effects in the lungs, reducing symptoms and preventing exacerbations.
Together, they improve lung function, prevent flare-ups, and provide convenient combined therapy.
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Seroxyn is a combination inhaler containing Salmeterol (long-acting β2-agonist) and Fluticasone Propionate (inhaled corticosteroid). It is used for:
Asthma – when regular treatment with inhaled corticosteroids alone is insufficient or when already controlled on both drugs
Chronic Obstructive Pulmonary Disease (COPD)
Not for relief of acute asthma attacks – use a rescue inhaler for sudden symptoms.
Inhaler: 2 puffs of 25 µg Salmeterol + 50/125/250 µg Fluticasone Propionate twice daily
Inhalation capsule: 50 µg Salmeterol + 100/250 µg Fluticasone twice daily; max 50/500 µg twice daily
2 puffs of 25 µg Salmeterol + 50 µg Fluticasone twice daily
Inhalation capsule: 50 µg Salmeterol + 100 µg Fluticasone twice daily
50 µg Salmeterol + 250 µg Fluticasone twice daily
Important:
Use inhaler daily, even when asymptomatic
Rinse mouth after each use to prevent oral thrush
Common:
Tremor, headache, palpitations, throat irritation, hoarseness, oral thrush
Rare/Serious:
Cardiac arrhythmias, paradoxical bronchospasm, hypersensitivity reactions, muscle cramps
Avoid β-blockers (may reduce effect or worsen asthma)
Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) may increase fluticasone exposure
Do not start during an asthma attack or unstable asthma
Use rescue inhaler for sudden symptoms
Paradoxical bronchospasm may occur – treat immediately
COPD patients: Increased risk of pneumonia; monitor symptoms
Long-term corticosteroid use may cause: adrenal suppression, decreased bone density, glaucoma, growth reduction in children
Use only if expected maternal benefit outweighs potential risk
Low absorption into bloodstream; likely low exposure in breast milk
Pressurised canister: Do not puncture, break, or incinerate
Store below 30°C, away from sunlight, heat, eyes, and children
Therapeutic Class: Long-acting β2-agonists + inhaled corticosteroids
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.